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    Jeffrey R. Moore, Ph.D. - Publications


    Greenberg, M., Watt, J., Mealy, T., Jones, M., Szczesna-Cordary, D.,  Moore, J., (2009) The Molecular  Effects of Skeletal Muscle Myosin Regulatory Light Chain Phosphorylation  Am J Physiol Regul Integr Comp Physiol [Epub ahead of print].

    Pant, K., Watt, J., Greenberg, M., Jones, M., Szczesna-Cordary, D., Moore, J., (2009) Removal of the Cardiac Myosin Regulatory Light Chain Increases Isometric Force Production. /FASEB J Accepted.


    Greenberg, M.J., Watt J.D., Jones, M., Kazmierczak, K., Szczesna-Cordary, D., Moore, J.,R., (2009).Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanicsand kinetics. J Mol Cell Cardiol. Jan;46(1):108-15.


    Greenberg, M., Wang, C-L., Lehman, W., Moore, J., (2008) Modulation of actin mechanics by caldesmon and tropomyosin. Cell Motility and Cytoskeleton. Feb;65(2):156-64


    Szczesna-Cordary, D., Jones, M., Moore, J., Watt, J., Kerrick, G., Xu, Y., Wang, Y., Wagg, C., and Lopaschuk, G. (2007) Myosin Regulatory Light Chain E22K Mutation Results in Decreased Cardiac Intracellular Calcium and Force Transients. FASEB J. Dec;21(14):3974-85.


    Debold, E., Schmitt, J., Moore, J., Patlak, J., Beck, S., Seidman, J., Seidman, C., Warshaw, D. (2007) Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse a-cardiac myosin in the laser trap assay. Am J Physiol Heart Circ Physiol. Mar 9; Jul;293(1):H284-91


    Moore, J., (2005) Stretch activation: Toward a molecular mechanism. in “Nature’s Versatile engine: Insect flight muscle Inside and Out”, Vigoreaux J., ed., Landes Bioscience Publishers.


    Moore, J., Krementsova, E., Trybus, K., Warshaw, D.,(2004) Is the myosin V neck a compliant lever?, J. Mus. Res. Cell Motil. 25(1):29-35.


    Irving T, Bhattacharya S, Tesic I, Moore, J., Farman, Simcox A, Vigoreaux J, Maughan D. (2001) Changes in myofibrillar structure and function produced by N-terminal deletion of the regulatory light chain in Drosophila. Submitted to J. Mus. Res. Cell Motil., 22(8):675-83.

    Moore, J., Krementsova E, Trybus K, Warshaw D. (2001) Myosin V exhibits a high duty cycle and large unitary displacement, J. Cell Biol.,155 (4): 625-635 .
    *See also Wells. W. (2001) “Myosin V: tight grip and big steps” J. Cell Biol.,155 (4): 495.

    Moore, J., Dickinson M, Vigoreaux J, Maughan D. (2000) The Effect of removing the N-terminal extension of the Drosophila Myosin Regulatory Light Chain Upon Flight Ability and the Contractile Dynamics of Indirect Flight Muscle. Biophys J. 78: 1431-1440.

    Vigoreaux J, Moore, J., Maughan D. (2000) Role of the elastic protein projectin in stretch activation and work output of Drosophila flight muscles. in “Elastic Filaments of the Cell”, Pollack G. and Granzier H, eds., Kluwer Academic/Plenum Publishers

    Moore, J., Vigoreaux J, Maughan D. (1999) The Projectin mutant bentD/+ has reduced stretch activation and altered indirect flight muscle kinetics.J. Mus. Res. Cell Motil. 20: 797-806.

    Maughan D, Moore, J., Vigoreaux J, Barnes B, Mulieri LA. (1998) Work production and work absorption in muscle strips from vertebrate cardiac and insect flight muscle fibers. Adv Exp Med Biol., 453:471-80

    Vigoreaux JO, Hernandez C, Moore, J., Ayer G, Maughan D. (1998) A genetic deficiency that spans the flightin gene of Drosophila melanogaster affects the ultrastructure and function of the flight muscles. J Exp Biol., 201 ( Pt 13):2033-44

    Dickinson MH, Hyatt CJ, Lehmann FO, Moore, J., Reedy MC, Simcox A, Tohtong R, Vigoreaux JO, Yamashita H, Maughan DW. (1997) Phosphorylation-dependent power output of transgenic flies: an integrated study. Biophys J.. 73(6):3122-34
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