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Seminar Series

Spring 2009 Spring 2008
Fall 2008 Fall 2007


Spring 2009

Department of Physiology and Biophysics Seminar Series
1:00-2:20pm,
NEW ROOM: 670 Albany St, Rm 107/108
Last update 5 February 2009

Please contact Dr. Haya Herscovitz (haya@bu.edu) with any questions.

DATE
SPEAKER
TITLE & HOST
01/13/09
Monte Krieger, Ph.D.
Dept. of Biology
MIT
Charting the Fate of the 'Good Cholesterol' - Characterization of the HDL receptor SR-BI and its influence on Coronary Heart Disease
01/20/09
Dawn Braseamle, Ph.D.
Dept. of Nutritional Sciences
Rutgers University
Lipid Droplet-Associated Proteins Control Triacylglycerol Metabolism
02/03/09
Mary Roberts, Ph.D.
Merkert Chemistry Center
Boston College
Akt and PTEN: the yin and yang of signaling
02/10/09

Jane Kondev, Ph.D.
Dept. of Physics
Brandeis Univ.
Geography of bacterial chromosomes
02/17/09
Sunney Xiaoliang Xie, Ph.D.
Dept. of Chemistry & Chem. Biol.
Harvard Univ.
Holding Life Processes up to the Light, at the Single-Molecule Level
2/24/09
Lila Geirasch, Ph.D.
Dept. of Biochem & Mol Biol, Dept of Chem
U Mass, Amherst
(Host: Dr. James McKnight)
FRIDAY
02/27/09
Alexey Ladokhin, Ph.D.
Dept. Biochem. & Mol. Biol.
Kansas Univ. Medical Center

Thermodynamics of pH-Triggered Membrane Protein Insertion: what can we learn about membrane protein stability?
(Host: Dr. Olga Gursky)

03/10/09
Adam Lerner, Ph.D.
Dept. Medicine & Pathology
Director, Hematology Training Pgm
Boston Univ. School of Medicine
Mechanistic studies of the anti-estrogen resistance gene AND-34/BCAR3
03/17/09
Lee Makowski, Ph.D.
Div. of Biological Sciences
Argonne National Lab
Linking the Protein Ensemble to Function
03/31/09
John Clardy, Ph.D.
Department of Biological Chemistry & Molecular Pharmacology
Harvard Medical School
What We Can Learn from Bugs
04/07/09
Stanley Hazen, Ph.D.
Dept. of Mol. Med.
Cleveland Clinic, Lerner College of Medicine
Case Western Reserve Univ.
Myloperoxidase, HDL and PON1 - functional partners in atherosclerosis
(Host: Dr. Donald M. Small)
FRIDAY
04/17/09
9a-4:15p
Rm R115
STUDENT SEMINAR DAY Graduate Student Talks
FRIDAY
04/24/09
9a-4:15p
Rm R115
STUDENT SEMINAR DAY Graduate Student Talks
04/28/09
Dr. Mason W. Freeman
Lipid Metabolism Unit
Dept. of Medicine
Mass General Hospital / Harvard Medical School
ABCA Transporters: Lipid Movers and Shakers
(Host: Dr. David Atkinson)
05/05/09
Dr. Jim Delikatny
Assistant Director, Molecular Imaging Laboratory
Research Associate Professor, Dept. of Radiology
University of Pennsylvania
Probing lipid metabolism non-invasively with MR and optical imaging
(Host: Dr. David Atkinson)

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Fall 2008

Department of Physiology and Biophysics Seminar Series
1:00-2:20pm, room L301
Last update 12/04/2008

You may contact Dr. Haya Herscovitz (haya@bu.edu), the fall seminar coordinator, with any questions.

DATE
SPEAKER
TITLE & HOST
9/2/08
Christopher Gabel, PhD
Harvard University, Dept. Of Physics
Dept. of Physiology & Biophysics
"The Study of Neural Regeneration in C. Elegans Using Femtosecond Laser Surgery”
(Host: Dr. Andy Zoeller)
9/9/08
Alexei Kurakin, PhD
Beth Israel Deaconess Hospital
Medical Center
“Adaptice plasticity in protein interactions and cellular organization”
(Host: Dr. Andy Zoeller)
9/19/08
Friday
Hanna Rapaport, PhD
Ben-Gurion University of Negev
Dept. Biotechnology Engineering
“Structure of Amphiphilic Peptides at Interfaces”
(Host: Dr. Donald M. Small)
9/23/08

Rajesh Ramachandran, PhD
The Scripps Research Institute
Dept. Cell Biology - NEW DATE!
Fluorescence-detected dynamics of dynamin-membrane interactions in
clathrin-mediated endocytosis

(Host: Dr. Andy Zoeller)
10/07/08 
Kenneth Walsh, PhD,
BU School of Medicine,
Whitaker Cardiovascular Institute
TBA
(Host: Dr. William Lehman)
10/21/08
Laura Liscum, PhD
Tufts School of Medicine, Dept. Physiology
TBA
(Host: Haya Herscovitz and Barbara Schrieber)
10/28/08
Richard Cohen, PhD
BU School of Medicine, Vascular Biology
Oxidative post-translational modification of proteins and cellular function
(Host: Dr. Haya Herscovitz)
11/04/08
Matt Lang,Ph.D.
MIT
Advances in Single Molecule Biophysics, Studies of Actin Machinery and the Force Generation Mechanism of Kinesin
(Host: Dr. Haya Herscovitz and Michael Greenberg)
12/02/08
Alan Engelman, Ph.D.
Dept. of Pathology
Harvard Medical School
Integrase-Binding Co-factors and HIV-1 Infection
12/09/08
Charles Brenner, Ph.D.
Depts. of Genetics & Biochemistry & the Norris Cotton Cancer Center
Dartmouth Medical School
TBA
12/16/08
Lila Geirasch, Ph.D.
Dept. of Biochem & Mol Biol, Dept of Chem
U Mass, Amherst
POSTPONED due to weather (Host: Dr. James McKnight)

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Spring 2008

Department of Physiology and Biophysics Seminar Series
1:00-2:20pm, room L301

DATE
SPEAKER
TITLE & HOST
1/15/08
Dr. Karen Allen
Boston University School of Medicine
Dept. of Physiology & Biophysics
"Structural Enzymology”
1/22/08
Dr. Biju Pillai
Boston University School of Medicine
Dept. of Physiology & Biophysics
“How fast do very long chain saturated fatty acids flip and flop?”
(Host: Hamilton lab)
1/29/08
Dr. Krishna Murthy
University of Alabama at Birmingham
 “Structure of ApoA-1”
(Hosts: D. Atkinson, D. Small and G. Shipley)
2/12/08
Dr. Jonathan Goldberg
Memorial Sloan-Kettering
Cancer Center, New York
“Structure and Function of COPII Transport Vesicles”
(Hosts: G. Shipley, C. Akey)
2/26/08
Dr. M. Elizabeth Stroupe
Brandeis University
“Structural studies of splicing complexes”
(Host: E. Bullitt)
3/04/08
Dr. Barry Honig
Center for Computational Biology
and Bioinformatics
Columbia University, New York
“Relating Cellular to Molecular Specificity”
(Hosts: D. Small/D. Atkinson)
3/11/08
Dr. David Ron
Skirball Institute,
New York University Medical Center
“Physiological considerations in unfolded protein responses”
(Host: H. Herscovitz)
3/18/08
Dr. Rex F. Pratt, Ph.D.
Professor of Biochemistry
and Beach Professor of Chemistry
Wesleyan University
“Enzyme mechanisms”
(Host: K. Allen)
3/25/08
Hwai-Chen Guo, Ph.D.
BUSM
Glycosylasparaginase cis- to trans-hydrolysis of amide bonds
4/08/08
Dr. Martin Karplus
Harvard University,
Department of Chemistry
and Chemical Biology
“How Proteins Work: Insights from Simulations”
(Host: B. Lehman)
4/18/08
&
4/25/08
Student Seminar Days (Hosts: Drs. C. Akey, K. Allen)

4/29/08
Dr. Ramanujan Hegde
Cell Biology and Metabolism Branch
National Institute of Child Health and Human development (NIH)
Bethesda, MD 20892
“The biosynthesis of secretory and membrane proteins”
(Host: C. Akey)
5/06/08
Dr. Guangwei Du
SUNY, Stonybrook (NY)
Center for Developmental Genetics
Dept. of Pharmacology
“Lipid signal regulation of membrane trafficking and oncogenesis”
(Host: R.A. Zoeller)
Friday,
5/09/08
3:00pm
Room L303
Seemantini Nadkarni, PhD
Harvard Medical School
Massachusetts General Hospital
Wellman Center for Photomedicine
"Optical Techniques to Evaluate Atherosclerosis: a Multi-factorial Perspective"
(Host: R.A. Zoeller)
5/13/08
Dr. Mary Munson
UMass Medical Center
“The Exocyst Complex:  Molecular Architecture and Function in Exocytosis”
(Host: CJ McKnight)
5/20/08
Norman A. Mazer, M.D., PhD
Boston University School of Medicine
"A Physiologically-Based Mathematical Model of the Metabolic Clearance Rate of Testosterone"
(Host: D. Atkinson)

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Fall 2007

Department of Physiology and Biophysics Seminar Series
1:00-2:20pm, room L301

DATE
SPEAKER
TITLE & HOST
9/18/07 
Dr. Nicholas R. Silvaggi
Boston University School of Medicine
Dept. of Physiology & Biophysics
Structural Insights into Inhibition of the Clostridium botulinum Neurotoxin Serotype A Light Chain”
(Host: Allen lab)
9/25/07
Dr. David Cane, Professor
Brown University
Department of Chemistry
“Nature's Dirty Secrets”
(Host: K. Allen)
10/09/07
Dr. Alexey Onufriev
Assistant Professor
Departments of Computer Science and Physics, Virginia Tech
“Dynamics”
(Host: B. Lehman)
10/16/07
Dr. Tom Cronin
University of Maryland at Baltimore County in the Department of Biology
 “Color Madness:  The Evolution of Color and Polarization Vision in Mantis Shrimps”
(Host: C. Cornwall)
10/23/07
Dr. Jay Neitz
Department of Cell Biology, Neurobiology & Anatomy
Medical College of Wisconsin
http://mcw.edu/cellbio/colorvision/
“Evolutionary endgame for the eye” or “Welcome to the wonderful world of color: gene therapy for colorblindness in a primate”
(Host: C. Cornwall)
11/06/07
Dr. William Bachovchin
Tufts University
Biochemistry Department
Are enzymes templates or mechanical devices?”
(Host: J. Hamilton)
11/13/07
Dr. Michael Radermacher
Health Science Research Facility
Univ of Vermont Medical School
“The Structure of Complex I in the Mitochondrial Respiratory Chain”
(Host: C Akey)
11/27/07
Preethi Chandramouli
Boston University School of Medicine
Dept. of Physiology & Biophysics
“Structure of the 80S ribosome”
(Host: Akey lab)
12/04/07
Dr. Ernst J. Schaefer, MD
Director, Cardiovascular Research & Lipid Metabolism Laboratories & Lipid and Heart Disease Prevention Program Tufts University School of Medicine Friedman School of Nutrition Science & Policy
“The Metabolism of High Density Lipoprotein Particles”
(Host: J. Hamilton)
12/18/07
Dr. Jeff Hoch
Department of Molecular, Microbial,
and Structural Biology
University of Connecticut Health Center
http://structbio.uchc.edu/
HochLab_files/index.html
“Folding, Stability, and Structure of Human Prolactin”
(Host: CJ. McKnight)
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